Let’s be honest: when you hear the term fecal transplant, your first reaction probably isn’t awe-inspired curiosity. But when it comes to Microbiome Restorative Therapy (MBRT), a term coined by Dr. Margo Roman, suddenly we’re not just talking sh*t — we’re talking total gut ecosystem renovation.
MBRT vs FMT
MBRT is a multi-step, holistic approach to gut healing that includes (but goes far beyond) FMTs — fecal microbiota transplants. Where FMT is the act of introducing poop from a healthy donor into the gut of a recipient, MBRT treats the gut terrain like sacred soil: it preps it, clears it, plants new life, and nourishes it to thrive.
Think of it as landscaping for the microbiome. You don’t just throw seeds in a weed-ridden yard and expect a beautiful garden. MBRT is about tending the soil first. FMT is a part of MBRT, but MBRT is the whole package. It includes:
- Medical ozone therapy to remove harmful biofilms
- Nutraceutical support to prep the gut environment
- Microbiome-rich transplants from naturally reared, raw-fed, multi-generational healthy donor animals
FMT alone might bring temporary relief. MBRT aims for lasting transformation.
Ozone & Building the Terrain
Ozone therapy isn’t just a cool buzzword. It breaks down biofilms (the slimy barricades bacteria build to protect themselves) so the new microbiome can actually take root. Without clearing that film, you’re just politely tossing good bacteria into a house where they aren’t welcome and hoping they move in.
Dr. Roman uses medical ozone rectally before introducing the transplant, ensuring the colon is oxygen-rich and ready to receive new microbial tenants. You can use ozone therapy at home with the right equipment (some are even safe for pets and humans). It’s antibacterial, antifungal, antiviral, and it boosts cellular oxygen. Poop capsules alone won’t fix a wrecked gut. A truly successful MBRT protocol also includes:
- Fresh, species-appropriate diets (no glyphosate, processed feed, or chemical junk)
- Minimal vaccinations and toxins
- Avoidance of pesticides and flea/tick chemicals
- Herbal and homeopathic support
- A lifestyle that supports regeneration, not just relief
Conditions MBRT May Help
MBRT isn’t just for chronic diarrhea. Pet parents and practitioners have reported improvement in:
- Chronic gastrointestinal disorders
- Autoimmune disease
- Behavioral issues and anxiety
- Allergies and itching
- Inflammatory conditions
- Cancer co-management
- Hormonal imbalances (especially related to adrenal and thyroid function)
And yes, sometimes the results are dramatic. Like dogs going from aggression to affection. Or long-term diarrhea resolving after years of antibiotics. Every pet is an individual and will have their own transformation.
Pills, Powders, Slurries: What Form Is Best?
In a perfect world, fresh, raw transplants (administered rectally) are best. Next would be freeze-dried. Vet clinics that provide transplants often provide different options depending on your dog’s needs and comfort level. Capsules are convenient, but they’re not a magic bullet — especially if you aren’t supporting the gut terrain at the same time.
Regardless of the form the FMT takes, one of the secrets behind MBRT success is sourcing. Legacy microbiome FMT comes from raw-fed, antibiotic-free, multi-generational dogs. Dr. Roman’s donor animals, whose fecal material is sold by Legacy Biome, have never had antibiotics, are minimally vaccinated, and are raised holistically on clean land. That is what makes the difference.
Other FMT providers may have looser standards — one year without antibiotics isn’t the same as seven generations of naturally reared health. Ask questions. Where did the sample come from? Was the dog kibble-fed? Has it had chemical flea treatments? This is important and could make the difference between a successful therapy or a waste of time and money.
A Note on the Terrain
If you take anything from this post, let it be this: nurture the terrain. The gut needs:
- The right pH
- Minimal inflammation
- An absence of chemicals
- Nutrient-dense food
Otherwise, even the best poop in the world is going to say, “Nope, not staying in this shi*t hole!” If you’re interested in MBRT, I would absolutely check Legacy Biome for products and mbrt.life for education. They’re top of the line and have the best products. Work with a practitioner who understands ozone, nutrition, and gut health. Be sure to ditch the processed foods and chemicals to restore first, then repopulate.
In the End, It’s Not Just Good Sh*t
MBRT is more than just an upgraded poop protocol. It’s a deep, thoughtful, systems-based approach to restoring health from the inside out. The gut is the foundation — and a future of wellness depends on it.
Sure, it might start with poop! But it ends with transformation. Let the gut lead the way. 🌱
About Dr. Margo Roman
Dr. Margo Roman, DVM, is a pioneer in integrative veterinary medicine and the founder of Microbiome Restorative Therapy (MBRT). With over 40 years of experience, she has dedicated her career to revolutionizing pet health through holistic and innovative therapies. Dr. Roman’s seven generations of naturally reared, antibiotic-free dogs serve as the donor foundation for Legacy Biome, offering some of the purest microbiome material available. Beyond her clinical work, Dr. Roman is a passionate advocate for sustainable living, minimal chemical exposure, and changing outdated veterinary regulations to better serve animal health. She continues to educate the public and the veterinary community with her research, international lectures, and forthcoming books on ozone therapy and MBRT.
